A Milanese café entirely designed by the American director Wes Anderson.

A fairy tale castle in modern Rome.

This ritzy Italian market is built around a statue of an unforgiven heretic who was burned for his belief in an endless universe.

A burial vault located under Tiber Island in the middle of the Italian capital.

One of the most important yet well-hidden museums dedicated to the history of medicine.

The crypts of Capuchin friars decorated with the bones of over 4,000 friars, including an entire "crypt of pelvises."

An incredible menagerie of more than 3 million taxidermied animals at the oldest science museum in Europe.

The graveyard is filled with beautiful funerary art and boasts breathtaking views of Florence.

Renaissance villa and gardens complete with a tormented colossus.

This shining multicolored metro station deep under Naples is said to be the most beautiful in Europe.

Dug as a secret royal escape route, the tunnel became a wartime bomb shelter and dumping ground for vintage cars.

Next to the Leaning Tower of Pisa is a cemetery home to ancient sarcophagi and disturbing murals.

The first botanical garden, a feather in the cap of the Grand Duke of Tuscany.

Anatomical cabinet holds unexpected treasures.

Drink wine handed out through a window as part of an age-old tradition.

Overlooked amid the tourist bustle of Florence, this museum is dedicated to the craft of stone inlay.

The mummified relic of St. Antoninus.

The oldest operating pharmacy in the world features 800-year-old recipes.

This picturesque Umbrian city has a subterranean side that has long remained hidden.

The hotel where Martin Luther King Jr. was shot is now a museum dedicated to his work.

This Wild West attraction is probably more fiction than history, but that doesn't mean it's not awesome.

This abandoned prison castle has become an imposing gallery of graffiti art.

This modern antique shop is a museum for 1980's Saturday morning cartoon culture.

This sidewalk tribute honors Colorado's great culinary creation.